Tg(Ela1-TVA)#Bcl
Transgene Detail

Summary

• Symbol: Tg(Ela1-TVA)#Bcl
• Name: transgene insertion #, Brian C Lewis
• MGI ID: MGI:3531077
• Synonyms: elastase-tv-a
• Transgene: Tg(Ela1-TVA)#Bcl Location: unknown
• Alliance: Tg(Ela1-TVA)#Bcl page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: An 800 bp cDNA encoding the TVA cDNA was flanked by the rat elastase 1 promoter and intron and polyA sequences from SV40. The transgene was expressed throughout the pancreas in newborn mice, but expression became localized to the acini in the adult pancreas. Expression was not detected in the liver, spleen, lung, or kidney. (J:87197)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Ela1-TVA)#Bcl

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:87197 Lewis BC, et al., The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Genes Dev. 2003 Dec 15;17(24):3127-38
• All: 3 reference(s)