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Gene trapped Allele Detail
Symbol: IdeGt(OST132429)Lex
Name: insulin degrading enzyme; gene trap OST132429, Lexicon Genetics
MGI ID: MGI:3530576
Synonyms: IDE-, IdeGt(neo)486Lex, IdeGt(VICTR20)19Lex
Gene: Ide  Location: Chr19:37268743-37337852 bp, - strand  Genetic Position: Chr19, 32.24 cM
Mutant Cell Line:  OST132429
Germline Transmission:  Earliest citation of germline transmission: J:82747
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
Mutation detailsA gene trap vector consisting of LTR sites flanking a Beta-geo cassette containing a splice acceptor and a PGK-puromycin resistance cassette containing a splice donor integrated into intron 1. No mRNA was found in the liver of homozygotes when analyzed by RT-PCR. Western blot confirmed lack of protein. (J:82747)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Ide Mutation:  45 strains or lines available
See also, data as provided by Lexicon Genetics, Inc.
Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory