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IdeGt(OST132429)Lex
Gene trapped Allele Detail
Nomenclature
Symbol: IdeGt(OST132429)Lex
Name: insulin degrading enzyme; gene trap OST132429, Lexicon Genetics
MGI ID: MGI:3530576
Synonyms: IDE-, IdeGt(neo)486Lex, IdeGt(VICTR20)19Lex
Gene: Ide  Location: Chr19:37268741-37334544 bp, - strand  Genetic Position: Chr19, 32.24 cM
Mutation
origin
Mutant Cell Line:  OST132429
Germline Transmission:  Earliest citation of germline transmission: J:82747
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA gene trap vector consisting of LTR sites flanking a Beta-geo cassette containing a splice acceptor and a PGK-puromycin resistance cassette containing a splice donor integrated into intron 1. No mRNA was found in the liver of homozygotes when analyzed by RT-PCR. Western blot confirmed lack of protein. (J:82747)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Ide Mutation:  20 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory