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Cacna1gtm1.1Stl
Targeted Allele Detail
Nomenclature
Symbol: Cacna1gtm1.1Stl
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit; targeted mutation 1.1, Susumu Tonegawa
MGI ID: MGI:3530501
Synonyms: alpha1G KO
Gene: Cacna1g  Location: Chr11:94408391-94474100 bp, - strand  Genetic Position: Chr11, 58.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96099
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCacna1gtm1Stl mice were crossed with mice expressing cre in the germ line and produced this allele in which exons 9-12 were removed. In situ hybridization of mutant brains confirmed the complete loss of transcript. (J:96099)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1g Mutation:  36 strains or lines available
References
Original:  J:96099 Anderson MP, et al., Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1743-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory