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Frat2tm2Brn
Targeted Allele Detail
Nomenclature
Symbol: Frat2tm2Brn
Name: frequently rearranged in advanced T cell lymphomas 2; targeted mutation 2, Anton Berns
MGI ID: MGI:3530463
Gene: Frat2  Location: Chr19:41845978-41848132 bp, - strand  Genetic Position: Chr19, 35.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96034
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 18 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Frat2 Mutation:  3 strains or lines available
Notes

To generate Frat1/Frat2 double mutant mice, Frat1tm1Brnheterozygous ES cells were targeted with the Frat2 knockout construct.

References
Original:  J:96034 van Amerongen R, et al., Frat is dispensable for canonical Wnt signaling in mammals. Genes Dev. 2005 Feb 15;19(4):425-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory