Gjc1tm1.1Weil
Targeted Allele Detail
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Symbol: |
Gjc1tm1.1Weil |
Name: |
gap junction protein, gamma 1; targeted mutation 1.2, Reto Weiler |
MGI ID: |
MGI:3530295 |
Synonyms: |
Cx45del[EGFP] |
Gene: |
Gjc1 Location: Chr11:102690405-102710526 bp, - strand Genetic Position: Chr11, 66.48 cM
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Alliance: |
Gjc1tm1.1Weil page
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Germline Transmission: |
Earliest citation of germline transmission:
J:95984
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Parent Cell Line: |
HM-1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd-Hprt1b-m3
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Crossing Gja7tm1Weil with mice expressing cre in the germ line resulted in the excision of exon 3 by cre mediated recombination, leaving a single loxP site and an EGFP.
(J:95984)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gjc1 Mutation: |
33 strains or lines available
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Original: |
J:95984 Maxeiner S, et al., Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission. J Neurosci. 2005 Jan 19;25(3):566-76 |
All: |
1 reference(s) |
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