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Srsf1tm1.1Xdfu
Targeted Allele Detail
Nomenclature
Symbol: Srsf1tm1.1Xdfu
Name: serine and arginine-rich splicing factor 1; targeted mutation 1.1, Xiang-Dong Fu
MGI ID: MGI:3530159
Synonyms: ASF/SF2-
Gene: Srsf1  Location: Chr11:88047373-88053755 bp, + strand  Genetic Position: Chr11, 52.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96039
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is produced from Sfrs1tm1Xdfu through cre recombinase in the oocyte resulting in deletion of exons 2 - 4 in the germline. (J:96039)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Srsf1 Mutation:  63 strains or lines available
References
Original:  J:96039 Xu X, et al., ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 2005 Jan 14;120(1):59-72
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory