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Rrm2bGt(OST85254)Lex
Gene trapped Allele Detail
Nomenclature
Symbol: Rrm2bGt(OST85254)Lex
Name: ribonucleotide reductase M2 B (TP53 inducible); gene trap OST85254, Lexicon Genetics
MGI ID: MGI:3529827
Synonyms: Rrm2bGt(neo)263Lex
Gene: Rrm2b  Location: Chr15:37923952-37961110 bp, - strand  Genetic Position: Chr15, 15.1 cM
Mutation
origin
Mutant Cell Line:  OST85254
Germline Transmission:  Earliest citation of germline transmission: J:94338
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA gene trap vector containing a neomycin selection cassette was inserted in intron 1 downstream of the ATG initiation site. RT-PCR analysis demonstrated absence of mRNA in kidney and spleen of homozygous mutant mice. (J:186071)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 22 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rrm2b Mutation:  16 strains or lines available
References
Original:  J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/17/2019
MGI 6.14
The Jackson Laboratory