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Apodtm1Bres
Targeted Allele Detail
Nomenclature
Symbol: Apodtm1Bres
Name: apolipoprotein D; targeted mutation 1, Jan L Breslow
MGI ID: MGI:3528149
Synonyms: ApoD-, Apodtm1Hhmd
Gene: Apod  Location: Chr16:31296192-31314808 bp, - strand  Genetic Position: Chr16, 21.41 cM
Increased myocardial infraction size following ischemia in Apodtm1Bres/Apodtm1Bres mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95654
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 2, including the translational start and signal peptide needed for protein secretion, with a neomycin resistance cassette. (J:101977)
Generation of the Apodtm1Bres allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apod Mutation:  7 strains or lines available
References
Original:  J:95654 Hildebrand MS, et al., Expression of the carrier protein apolipoprotein D in the mouse inner ear. Hear Res. 2005 Feb;200(1-2):102-114
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory