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Zbtb32tm1Ppp
Targeted Allele Detail
Nomenclature
Symbol: Zbtb32tm1Ppp
Name: zinc finger and BTB domain containing 32; targeted mutation 1, Pier Paolo Pandolfi
MGI ID: MGI:3527274
Synonyms: PLZP-
Gene: Zbtb32  Location: Chr7:30589681-30598909 bp, - strand  Genetic Position: Chr7, 18.72 cM, cytoband B2-B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95119
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region and 750 bp of 3' flanking sequence encompassing a CpG island was replaced with a neo. Northern blot of mutant testis confirmed the lack of transcript. (J:95119)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb32 Mutation:  6 strains or lines available
References
Original:  J:95119 Piazza F, et al., Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis. Mol Cell Biol. 2004 Dec;24(23):10456-69
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory