Tg(Pim1-E2F2)6Rebr
Transgene Detail
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Symbol: |
Tg(Pim1-E2F2)6Rebr |
Name: |
transgene insertion 6, Rene Bernards |
MGI ID: |
MGI:3527199 |
Synonyms: |
Eu-pp-E2F2, TEF2-6 |
Transgene: |
Tg(Pim1-E2F2)6Rebr Location: unknown
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Alliance: |
Tg(Pim1-E2F2)6Rebr page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Pim1-E2F2)6Rebr expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
E2F1 (1869) |
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Tg(Pim1-E2F2)6Rebr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pim1 (MGI:97584) |
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Mutation details: A human E2F2 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated immunoglobulin heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony Murine Leukemia Virus. The founder carrying this allele failed to transmit the transgene to any of its offspring.
(J:88864)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:88864 Scheijen B, et al., High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem. 2004 Mar 12;279(11):10476-83 |
All: |
1 reference(s) |
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