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Gad1tm1Rpa
Targeted Allele Detail
Nomenclature
Symbol: Gad1tm1Rpa
Name: glutamate decarboxylase 1; targeted mutation 1, Richard D Palmiter
MGI ID: MGI:3527168
Synonyms: Gad1lox
Gene: Gad1  Location: Chr2:70561765-70602014 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126581
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by loxP site and a frt-flanked neo cassette was inserted downstream of exon 2. The neo cassette was removed by Flp-mediated recombination. (J:126581)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:  18 strains or lines available
References
Original:  J:126581 Chattopadhyaya B, et al., GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron. 2007 Jun 21;54(6):889-903
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory