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Sod1tm1Ysh
Targeted Allele Detail
Nomenclature
Symbol: Sod1tm1Ysh
Name: superoxide dismutase 1, soluble; targeted mutation 1, Ye-Shih Ho
MGI ID: MGI:3526701
Synonyms: Sod1-
Gene: Sod1  Location: Chr16:90220742-90226322 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46672
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 was replaced with a neomycin resistance gene. mRNA could not be detected in the tissues of homozygous mice. (J:46672)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:  25 strains or lines available
References
Original:  J:46672 Ho YS, et al., Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J Biol Chem. 1998 Mar 27;273(13):7765-9
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory