Pcyt1a^tm1.1Irt
Targeted Allele Detail

Summary

• Symbol: Pcyt1a^tm1.1Irt
• Name: phosphate cytidylyltransferase 1, choline, alpha isoform; targeted mutation 1, Ira Tabas
• MGI ID: MGI:3526522
• Gene: Pcyt1a Location: Chr16:32249739-32293883 bp, + strand Genetic Position: Chr16, 22.69 cM
• Alliance: Pcyt1a^tm1.1Irt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97657
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was created from Pcyt1a^tm1Irt by crossing with TgN(ACTB-Cre)2Mrt which expresses cre under the control of the human beta actin promoter. (J:97657)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcyt1a Mutation: 27 strains or lines available

References

• Original: J:97657 Wang L, et al., Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Mol Cell Biol. 2005 Apr;25(8):3357-63
• All: 1 reference(s)