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Gene trapped Allele Detail
Symbol: MtrrGt(XG334)Byg
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase; gene trap XG334, BayGenomics
MGI ID: MGI:3526159
Synonyms: Mtrrgt, MtrrGt(pGT1Lxf)1Rgma, MtrrGt(pGT1Lxf)1Ucd
Gene: Mtrr  Location: Chr13:68560780-68582121 bp, - strand  Genetic Position: Chr13, 35.54 cM
Mutant Cell Line:  XG334 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:121477
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf
Mutation detailspGT1Lxf, containing En2 intron/exon with splice acceptor, beta-galactosidase and neomycin resistance cassettes (beta-geo), and SV40 polyA site and ampicillin resisitance, 41.0 cM, pGT1Lxf insertion in intron 9, betwee exons 9 and 10. Inserted exactly 398 bp downstream of exon 9 and approximately 1.5 Kb upstream of exon 10. (J:121477)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mtrr Mutation:  21 strains or lines available
Original:  J:121477 Elmore CL, et al., Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 2007 May;91(1):85-97
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory