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Hoxd1tm1Mrc
Targeted Allele Detail
Nomenclature
Symbol: Hoxd1tm1Mrc
Name: homeobox D1; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:3526155
Gene: Hoxd1  Location: Chr2:74762980-74765142 bp, + strand  Genetic Position: Chr2, 44.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170402
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted into exon 2. The absence of transcript expression was confirmed by in situ hybridization on dorsal root ganglia samples. (J:170402)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxd1 Mutation:  9 strains or lines available
References
Original:  J:170402 Guo T, et al., An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nat Neurosci. 2011 Jan;14(1):31-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory