Scnm1^tm1Mm
Targeted Allele Detail

Summary

• Symbol: Scnm1^tm1Mm
• Name: sodium channel modifier 1; targeted mutation 1, Miriam Meisler
• MGI ID: MGI:3525884
• Synonyms: Scnm1^flox
• Gene: Scnm1 Location: Chr3:95037030-95041285 bp, - strand Genetic Position: Chr3, 40.74 cM, cytoband F2
• Alliance: Scnm1^tm1Mm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141236
• Parent Cell Line: BL/6-III (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted downstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. The neo cassette was removed by germ line, flp mediated recombination leaving exons 3 through 5 floxed. (J:141236)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scnm1 Mutation: 17 strains or lines available

References

• Original: J:141236 Howell VM, et al., A Targeted Deleterious Allele of the Splicing Factor SCNM1 in the Mouse. Genetics. 2008 Nov;180(3):1419-27
• All: 1 reference(s)