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Cnga2tm1Reed
Targeted Allele Detail
Nomenclature
Symbol: Cnga2tm1Reed
Name: cyclic nucleotide gated channel alpha 2; targeted mutation 1, Randall R Reed
MGI ID: MGI:3525590
Synonyms: OCNC1-tau::lacZ
Gene: Cnga2  Location: ChrX:71991849-72010218 bp, + strand  Genetic Position: ChrX, 37.15 cM, cytoband A6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA fragment of the gene that encodes the amino acids 307 to the carboxy terminus was replaced with a construct containing an IRES followed by a tau/lacZ gene fusion. Cre mediated recombination removed the floxed neo cassette. The expression pattern of the reporter gene was shown to reflect the expression pattern of the endogenous gene. (J:77304)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cnga2 Mutation:  12 strains or lines available
References
Original:  J:77304 Zhao H, et al., X inactivation of the OCNC1 channel gene reveals a role for activity-dependent competition in the olfactory system. Cell. 2001 Mar 9;104(5):651-60
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/09/2018
MGI 6.12
The Jackson Laboratory