Cnga2^tm1Reed
Targeted Allele Detail

Summary

• Symbol: Cnga2^tm1Reed
• Name: cyclic nucleotide gated channel alpha 2; targeted mutation 1, Randall R Reed
• MGI ID: MGI:3525590
• Synonyms: OCNC1^-tau::lacZ
• Gene: Cnga2 Location: ChrX:71035455-71053824 bp, + strand Genetic Position: ChrX, 37.15 cM, cytoband A6
• Alliance: Cnga2^tm1Reed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77304
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A fragment of the gene that encodes the amino acids 307 to the carboxy terminus was replaced with a construct containing an IRES followed by a tau/lacZ gene fusion. Cre mediated recombination removed the floxed neo cassette. The expression pattern of the reporter gene was shown to reflect the expression pattern of the endogenous gene. (J:77304)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnga2 Mutation: 15 strains or lines available

References

• Original: J:77304 Zhao H, et al., X inactivation of the OCNC1 channel gene reveals a role for activity-dependent competition in the olfactory system. Cell. 2001 Mar 9;104(5):651-60
• All: 6 reference(s)