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Nfkbiztm1Mamo
Targeted Allele Detail
Nomenclature
Symbol: Nfkbiztm1Mamo
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; targeted mutation 1, Masami Morimatsu
MGI ID: MGI:3525252
Synonyms: MAIL-
Gene: Nfkbiz  Location: Chr16:55811375-55838899 bp, - strand  Genetic Position: Chr16, 33.65 cM, cytoband C1.2 - C1.3
Allergic dermatitis in Nfkbiztm1Mamo/Nfkbiztm1Mamo mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95040
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfkbiz Mutation:  1 strain or line available
References
Original:  J:95040 Shiina T, et al., Targeted disruption of MAIL, a nuclear IkappaB protein, leads to severe atopic dermatitis-like disease. J Biol Chem. 2004 Dec 31;279(53):55493-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory