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Tg(Dct-Grm1)ESzc
Transgene Detail
Nomenclature
Symbol: Tg(Dct-Grm1)ESzc
Name: transgene insertion E, Suzie Chen
MGI ID: MGI:3525118
Synonyms: Tg(Grm1)EPv
Transgene: Tg(Dct-Grm1)ESzc  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Dct-Grm1)ESzc expresses 1 gene
 
Mutation detailsThe promoter from the mouse Dct gene (-3181 to + 445) drove the expression of the mouse Grm1 coding sequence corresponsing to -105 to + 4164. The polyA tail in the construct was from the human GH gene. Strong transgene expression was detected in mice carrying this allele. (J:83183)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:83183 Pollock PM, et al., Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia. Nat Genet. 2003 May;34(1):108-12
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory