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Abca1tm1Blt
Targeted Allele Detail
Nomenclature
Symbol: Abca1tm1Blt
Name: ATP-binding cassette, sub-family A (ABC1), member 1; targeted mutation 1, Horst Bluethmann
MGI ID: MGI:3525100
Gene: Abca1  Location: Chr4:53030787-53159895 bp, - strand  Genetic Position: Chr4, 28.57 cM, cytoband A5-B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95088
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a neomycin resistance cassette into exon 2 disrupted the gene. (J:95088)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abca1 Mutation:  9 strains or lines available
References
Original:  J:95088 Nofer JR, et al., Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease). J Biol Chem. 2004 Aug 6;279(32):34032-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory