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Tg(APPswe,PSEN1dE9)85Dbo
Transgene Detail
Nomenclature
Symbol: Tg(APPswe,PSEN1dE9)85Dbo
Name: transgene insertion 85, David R Borchelt
MGI ID: MGI:3524957
Synonyms: APdE9, APP-PS1, APP/PS1, APPswe/PS1dE9, APPswe/PS1deltaE9, Mo/Hu APPswe PS1dE9
Transgene: Tg(APPswe,PSEN1dE9)85Dbo  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Mice carrying this double transgene develop beta-amyloid deposits in the brain by 6 to 7 months of age.

References
Original:  J:78664 Jankowsky JL, et al., Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. Biomol Eng. 2001 Jun;17(6):157-65
All:  211 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory