Tg(KRT18-lacZ)1Jh
Transgene Detail

Summary

• Symbol: Tg(KRT18-lacZ)1Jh
• Name: transgene insertion 1, Jim Hu
• MGI ID: MGI:3522673
• Synonyms: K18mTELacZ
• Transgene: Tg(KRT18-lacZ)1Jh Location: unknown
• Alliance: Tg(KRT18-lacZ)1Jh page

Transgene origin

• Strain of Origin: C57BL/6 and SJL

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains the promoter, first intron and 5' untranslated region of the human keratin 18 gene and the 34-bp alpha mosaic virus transcriptional enhancerdriving the expression of a beta-galactosidase gene that contains an SV40 large T antigen nuclear localization signal. X-gal staining analysis indicated that expression occurs in the airway epithelium of transgenic mice. (J:94886)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

This transgene is representative of many lines and embryos created; these were not distinguished in the original reference.

References

• Original: J:94886 Chow YH, et al., Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14695-700
• All: 2 reference(s)