About   Help   FAQ
Park7tm1Cai
Targeted Allele Detail
Nomenclature
Symbol: Park7tm1Cai
Name: Parkinson disease (autosomal recessive, early onset) 7; targeted mutation 1, Hubaibin Cai
MGI ID: MGI:3522482
Gene: Park7  Location: Chr4:150897133-150914437 bp, - strand  Genetic Position: Chr4, 81.52 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141628
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first coding exon was replaced with a selection marker flanked with loxp sites. QPCR and Western blot analysis confirmed the absence of gene products. (J:141628)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Park7 Mutation:  46 strains or lines available
References
Original:  J:141628 Chandran JS, et al., Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiol Dis. 2008 Mar;29(3):505-14
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/12/2018
MGI 6.12
The Jackson Laboratory