Avpr1b^tm1Wsy
Targeted Allele Detail

Summary

• Symbol: Avpr1b^tm1Wsy
• Name: arginine vasopressin receptor 1B; targeted mutation 1, W Scott Young III
• MGI ID: MGI:3522438
• Synonyms: Avpr1b-, Avpr1b KO, V1bR^-
• Gene: Avpr1b Location: Chr1:131526977-131539738 bp, + strand Genetic Position: Chr1, 57.09 cM, cytoband E4
• Alliance: Avpr1b^tm1Wsy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94939
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region from the initiating codon until just before transmembrane region VI was eliminated. (J:94939)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Avpr1b Mutation: 33 strains or lines available

References

• Original: J:94939 Wersinger SR, et al., Vasopressin V1b receptor knockout reduces aggressive behavior in male mice. Mol Psychiatry. 2002;7(9):975-84
• All: 16 reference(s)