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Myh9tm1Maco
Targeted Allele Detail
Nomenclature
Symbol: Myh9tm1Maco
Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 1, Mary Anne Conti
MGI ID: MGI:3522434
Synonyms: A-
Gene: Myh9  Location: Chr15:77760587-77842175 bp, - strand  Genetic Position: Chr15, 36.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94940
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-neomycin cassette was inserted in exon 3. Absence of gene products was confirmed by Northern and Western blot analysis and by immunohistochemistry. (J:94940)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myh9 Mutation:  187 strains or lines available
References
Original:  J:94940 Conti MA, et al., Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem. 2004 Oct 1;279(40):41263-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory