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Zbtb32tm1Iho
Targeted Allele Detail
Nomenclature
Symbol: Zbtb32tm1Iho
Name: zinc finger and BTB domain containing 32; targeted mutation 1, I-Cheng Ho
MGI ID: MGI:3522354
Synonyms: ROGKO
Gene: Zbtb32  Location: Chr7:30589681-30598909 bp, - strand  Genetic Position: Chr7, 18.72 cM, cytoband B2-B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94944
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-5 and part of exon 6 were replaced with a neomycin resistance gene. Absence of protein product was confirmed via immunohistochemistry studies. (J:94944)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb32 Mutation:  6 strains or lines available
References
Original:  J:94944 Kang BY, et al., ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Mol Cell Biol. 2005 Jan;25(2):554-62
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory