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Tg(Gfap-cre)73.12Mvs
Transgene Detail
Nomenclature
Symbol: Tg(Gfap-cre)73.12Mvs
Name: transgene insertion 73.12, Michael V Sofroniew
MGI ID: MGI:3522215
Synonyms: GFAP-Cre, mGFAPCre, mGFAP-Cre
Transgene: Tg(Gfap-cre)73.12Mvs  Location: unknown  
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6NHsd)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe bacterial Cre recombinase gene was inserted into the first exon of an expression cassette (clone 445) that contains all the introns, promoter regulatory elements, exons, and 2.5 kb of 5' and 2 kb of 3' flanking DNA of the astroglia-specific mouse glial fibrillary acidic protein gene. GFAP is not expressed from the transgene due to deletion of part of exon 1. (J:94543)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gfap     Summary of all recombinase alleles driven by Gfap. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:94543 Garcia AD, et al., GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci. 2004 Nov;7(11):1233-41
All:  58 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory