Notch2^tm1Rko
Targeted Allele Detail

Summary

• Symbol: Notch2^tm1Rko
• Name: notch 2; targeted mutation 1, Raphael Kopan
• MGI ID: MGI:3522155
• Synonyms: N2^flox
• Gene: Notch2 Location: Chr3:97920854-98057683 bp, + strand Genetic Position: Chr3, 42.42 cM
• Alliance: Notch2^tm1Rko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94517
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Not Specified
• The molecular details of this allele are not published.

Expression

In Mice Carrying this Mutation:

52041 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Notch2 Mutation: 97 strains or lines available

References

• Original: J:94517 Pan Y, et al., gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell. 2004 Nov;7(5):731-43
• All: 13 reference(s)