About   Help   FAQ
Targeted Allele Detail
Symbol: Gapdhstm1Dao
Name: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; targeted mutation 1, Deborah A O'Brien
MGI ID: MGI:3522094
Synonyms: Gapds-
Gene: Gapdhs  Location: Chr7:30729775-30743681 bp, - strand  Genetic Position: Chr7, 19.23 cM, cytoband A3
Germline Transmission:  Earliest citation of germline transmission: J:94734
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 5 and part of exon 6 were replaced with a neo cassette. Western blot showed the absence of protein in mutant testis and sperm. (J:94734)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gapdhs Mutation:  10 strains or lines available
Original:  J:94734 Miki K, et al., Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16501-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory