Del(11Cops3-Rnf112)1Jrl
Targeted Allele Detail
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Symbol: |
Del(11Cops3-Rnf112)1Jrl |
Name: |
deletion, Chr 11, James R Lupski 1 |
MGI ID: |
MGI:3521985 |
Synonyms: |
Del(11Csn3-Zfp179)1Jrl, Del1Jrl, df(11)17 |
Gene: |
Del(11Cops3-Rnf112)1Jrl Location: Chr11:59708621-61344957 bp Genetic Position: Chr11, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:83302
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Parent Cell Line: |
AB2.2 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1b-m2
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Intergenic deletion, Intragenic deletion
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Del(11Cops3-Rnf112)1Jrl involves 77 genes/genome features (Gm26837, Gm24945, Gm27511 ...)
View all
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Mutation details: A deletion between Cops3 and Rnf112 was engineered in ES cells by targeted insertion of complementary partial Hprt-loxP constructs at each site. Cre recombinase actived deleted the intervening region and reconstructed the Hprt minigene for selection purposes.
(J:83302)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Del(11Cops3-Rnf112)1Jrl Mutation: |
1 strain or line available
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Original: |
J:83302 Walz K, et al., Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol Cell Biol. 2003 May;23(10):3646-55 |
All: |
8 reference(s) |
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