Neil3^tm1Yun
Targeted Allele Detail

Summary

• Symbol: Neil3^tm1Yun
• Name: nei like 3 (E. coli); targeted mutation 1, Yusaku Nakabeppu
• MGI ID: MGI:3521920
• Gene: Neil3 Location: Chr8:54039902-54092100 bp, - strand Genetic Position: Chr8, 29.14 cM
• Alliance: Neil3^tm1Yun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146662
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette. Immunoprecipitation experiments on thymocytes and splenocytes derived from homozygous mice confirmed that no detectable protein product is expressed from this allele. (J:146662)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Neil3 Mutation: 26 strains or lines available

References

• Original: J:146662 Torisu K, et al., Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein. J Biochem. 2005 Dec;138(6):763-72
• All: 2 reference(s)