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Neil3tm1Yun
Targeted Allele Detail
Nomenclature
Symbol: Neil3tm1Yun
Name: nei like 3 (E. coli); targeted mutation 1, Yusaku Nakabeppu
MGI ID: MGI:3521920
Gene: Neil3  Location: Chr8:53586867-53639065 bp, - strand  Genetic Position: Chr8, 29.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146662
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exon 1 with a neomycin resistance cassette. Immunoprecipitation experiments on thymocytes and splenocytes derived from homozygous mice confirmed that no detectable protein product is expressed from this allele. (J:146662)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neil3 Mutation:  11 strains or lines available
References
Original:  J:146662 Torisu K, et al., Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein. J Biochem. 2005 Dec;138(6):763-72
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/06/2017
MGI 6.10
The Jackson Laboratory