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Mgat1tm2Jxm
Targeted Allele Detail
Nomenclature
Symbol: Mgat1tm2Jxm
Name: mannoside acetylglucosaminyltransferase 1; targeted mutation 2, Jamey Marth
MGI ID: MGI:3514311
Synonyms: Mgat1F
Gene: Mgat1  Location: Chr11:49244191-49263027 bp, + strand  Genetic Position: Chr11, 29.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94770
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Homologous recombination was used to flank the single coding exon with loxP sites. (J:94770)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgat1 Mutation:  10 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Premature Ovarian Failure J:125880, J:237228.
References
Original:  J:94770 Ye Z, et al., N-glycan branching requirement in neuronal and postnatal viability. Glycobiology. 2004 Jun;14(6):547-58
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory