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Targeted Allele Detail
Symbol: Park7tm1Tmd
Name: Parkinson disease (autosomal recessive, early onset) 7; targeted mutation 1, Ted Dawson
MGI ID: MGI:3514165
Synonyms: DJ-1-
Gene: Park7  Location: Chr4:150897133-150914437 bp, - strand  Genetic Position: Chr4, 81.52 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:125021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/SvEv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA floxed neomycin resistance cassette replaced part of exon 2 and all of exon 3. Absence of protein product was confirmed by immunohistochemistry and western blot analysis. (J:125021)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Park7 Mutation:  46 strains or lines available
Original:  J:125021 Andres-Mateos E, et al., DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14807-12
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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