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Tg(Nkx2-5-cre)9Eno
Transgene Detail
Nomenclature
Symbol: Tg(Nkx2-5-cre)9Eno
Name: transgene insertion 9, Eric N Olson
MGI ID: MGI:3514028
Synonyms: Nk9, Nkx2.5Cre, Nkx2.5::Cre
Transgene: Tg(Nkx2-5-cre)9Eno  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA 2.5 kb fragment containing the mouse Nkx2.5 basal promoter and cardiac enhancer was placed in front of an NLS-cre cassette. Expression of cre is seen in developing heart, pharynx, and some liver cells. Three lines were created and line 9, which had the highest levels of cre recombination in the heart, was selected for use. (J:94514)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nkx2-5     Summary of all recombinase alleles driven by Nkx2-5.
 

Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:94514 McFadden DG, et al., The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005 Jan;132(1):189-201
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory