Tg(Nkx2-5-cre)9Eno
Transgene Detail
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Symbol: |
Tg(Nkx2-5-cre)9Eno |
Name: |
transgene insertion 9, Eric N Olson |
MGI ID: |
MGI:3514028 |
Synonyms: |
Nk9, Nkx2.5Cre, Nkx2.5-Cre, Nkx2.5::Cre |
Transgene: |
Tg(Nkx2-5-cre)9Eno Location: unknown
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Alliance: |
Tg(Nkx2-5-cre)9Eno page
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Ultrastructural nuclear abnormalities in Syne1tm1Chen/Syne1tm1Chen Syne2tm1.1ChenSyne2tm1.1Chen Tg(Nkx2-5-cre)9Eno/? cardiomyocytes
Show the 2 phenotype image(s) involving this allele.
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Nkx2-5-cre)9Eno expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Nkx2-5 (MGI:97350) |
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Mutation details: A 2.5 kb fragment containing the mouse Nkx2.5 basal promoter and cardiac enhancer was placed in front of an NLS-cre cassette. Expression of cre is seen in developing heart, pharynx, and some liver cells. Three lines were created and line 9, which had the highest levels of cre recombination in the heart, was selected for use.
(J:94514)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Nkx2-5
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:94514 McFadden DG, et al., The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005 Jan;132(1):189-201 |
All: |
23 reference(s) |
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