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Transgene Detail
Symbol: Tg(Alb1-a)83Ejmi
Name: transgene insertion 83, Edward J Michaud
MGI ID: MGI:3512795
Synonyms: alb-agouti 83, Tg(Alb1-a)83R
Transgene: Tg(Alb1-a)83Ejmi  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(Alb1-a)83Ejmi expresses 1 gene
Mutation detailsThe wild-type murine agouti cDNA was cloned into an expression cassette involving the mouse Alb1 promoter and SV40 poly A sequences. This cassette was cloned into fertilized FVB/N oocytes and hemizygous mice were maintained on an FVB/N background. This allele was derived from founder 83. Northern blot analysis confirmed transgene expression in the liver. No expression was detected in muscle, small intestine, brain or white adipose tissue. (J:90795)
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:90795 Kuklin AI, et al., Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes. Mol Cancer. 2004 Jun 2;3(1):17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory