Tg(HBVX)9Gja
Transgene Detail
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Symbol: |
Tg(HBVX)9Gja |
Name: |
transgene insertion 9, Gilbert Jay |
MGI ID: |
MGI:3512676 |
Synonyms: |
H9, HBx H9 |
Transgene: |
Tg(HBVX)9Gja Location: unknown
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Alliance: |
Tg(HBVX)9Gja page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: A 1.15 kb bragment of HBV subtype adr spanning nucleotides 707-1856 of the viral genome was cloned into CD-1 fertilized eggs. This DNA segment contains the entire coding region of the HBx gene, transcriptional enhancer sequence, principal RNA start sites and a polyA site. Northern blot analysis confirmed transgene expression in the liver, kidney and testis. This allele is associated with founder line H9.
J:90881 further defined this allele as carrying 5 copies of the transgene.
(J:78178)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:78178 Kim CM, et al., HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature. 1991 May 23;351(6324):317-20 |
All: |
2 reference(s) |
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