About   Help   FAQ
Tgfbr2tm1Sjkm
Targeted Allele Detail
Nomenclature
Symbol: Tgfbr2tm1Sjkm
Name: transforming growth factor, beta receptor II; targeted mutation 1, Seong-Jin Kim
MGI ID: MGI:3512546
Synonyms: HT, TbetaR-II
Gene: Tgfbr2  Location: Chr9:116087695-116175363 bp, - strand  Genetic Position: Chr9, 68.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71591
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 of Tgfbr2 was disrupted by using a phosphoglycerate kinase-neo cassette. Gene targeting was confirmed by Northern blot analysis. (J:71591)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfbr2 Mutation:  7 strains or lines available
References
Original:  J:71591 Im YH, et al., Heterozygous mice for the transforming growth factor-beta type ii receptor gene have increased susceptibility to hepatocellular carcinogenesis. Cancer Res. 2001 Sep 15;61(18):6665-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/18/2020
MGI 6.14
The Jackson Laboratory