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Targeted Allele Detail
Symbol: Tgfbr2tm1Sjkm
Name: transforming growth factor, beta receptor II; targeted mutation 1, Seong-Jin Kim
MGI ID: MGI:3512546
Synonyms: HT, TbetaR-II
Gene: Tgfbr2  Location: Chr9:116087695-116175363 bp, - strand  Genetic Position: Chr9, 68.39 cM
Germline Transmission:  Earliest citation of germline transmission: J:71591
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsExon 2 of Tgfbr2 was disrupted by using a phosphoglycerate kinase-neo cassette. Gene targeting was confirmed by Northern blot analysis. (J:71591)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfbr2 Mutation:  7 strains or lines available
Original:  J:71591 Im YH, et al., Heterozygous mice for the transforming growth factor-beta type ii receptor gene have increased susceptibility to hepatocellular carcinogenesis. Cancer Res. 2001 Sep 15;61(18):6665-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory