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Smad2tm1.3Mwst
Targeted Allele Detail
Nomenclature
Symbol: Smad2tm1.3Mwst
Name: SMAD family member 2; targeted mutation 1.3, Michael Weinstein
MGI ID: MGI:3512450
Synonyms: Smad2neodeltaE9,10
Gene: Smad2  Location: Chr18:76241580-76310963 bp, + strand  Genetic Position: Chr18, 51.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94232
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCrossing Smad2tm1Mwst with EIIa-cre mice caused the excision of exons 9 and 10, while leaving the loxP flanked PGK-neo. (J:94232)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad2 Mutation:  16 strains or lines available
References
Original:  J:94232 Liu Y, et al., Generation of novel conditional and hypomorphic alleles of the Smad2 gene. Genesis. 2004 Oct;40(2):118-123
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory