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Npdc1tm1Ce
Targeted Allele Detail
Nomenclature
Symbol: Npdc1tm1Ce
Name: neural proliferation, differentiation and control 1; targeted mutation 1, C Evrard
MGI ID: MGI:3512311
Gene: Npdc1  Location: Chr2:25399351-25409494 bp, + strand  Genetic Position: Chr2, 17.23 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94137
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsBeta-galactosidase and neomycin resistance genes were inserted in frame into exon 2 and an AU-rich degradation sequence was inserted 3' of the stop codon. Northern blot using as a probe a fragment corresponding to exon 1 indicated a lack of transcript in mutants. (J:94137)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Npdc1 Mutation:  18 strains or lines available
References
Original:  J:94137 Evrard C, et al., Functional analysis of the NPDC-1 gene. Gene. 2004 Dec 8;343(1):153-63
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory