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Targeted Allele Detail
Symbol: Acvr1ctm1Cfi
Name: activin A receptor, type IC; targeted mutation 1, Carlos F Ibanez
MGI ID: MGI:3512292
Synonyms: ALK7-
Gene: Acvr1c  Location: Chr2:58267453-58357895 bp, - strand  Genetic Position: Chr2, 33.05 cM
Germline Transmission:  Earliest citation of germline transmission: J:94135
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA lacZ reporter gene replaced 739 bp including part of the first exon and intron. No mRNA or protein were detected by RT-PCR or immunoreactivity in the pancreas. LacZ expression was detected in multiple organs (J:94135)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Acvr1c Mutation:  28 strains or lines available
Original:  J:94135 Jornvall H, et al., ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse. Mol Cell Biol. 2004 Nov;24(21):9383-9
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory