About   Help   FAQ
Acvr1ctm1Cfi
Targeted Allele Detail
Nomenclature
Symbol: Acvr1ctm1Cfi
Name: activin A receptor, type IC; targeted mutation 1, Carlos F Ibanez
MGI ID: MGI:3512292
Synonyms: ALK7-
Gene: Acvr1c  Location: Chr2:58267453-58357895 bp, - strand  Genetic Position: Chr2, 33.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94135
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ reporter gene replaced 739 bp including part of the first exon and intron. No mRNA or protein were detected by RT-PCR or immunoreactivity in the pancreas. LacZ expression was detected in multiple organs (J:94135)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Acvr1c Mutation:  28 strains or lines available
References
Original:  J:94135 Jornvall H, et al., ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse. Mol Cell Biol. 2004 Nov;24(21):9383-9
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/26/2019
MGI 6.14
The Jackson Laboratory