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Targeted Allele Detail
Symbol: Cdk2ap1tm1Dtw
Name: CDK2 (cyclin-dependent kinase 2)-associated protein 1; targeted mutation 1, David T Wong
MGI ID: MGI:3512185
Gene: Cdk2ap1  Location: Chr5:124345417-124363082 bp, - strand  Genetic Position: Chr5, 63.53 cM
Craniofacial abnormality of surviving Cdk2ap1tm1Dtw/Cdk2ap1tm1Dtw and Cdk2ap1tm1Dtw/Cdk2ap1+ mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:146277
Parent Cell Line:  LW1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2 and 3 were replaced with a cystosine deaminase and neo cassette. (J:146277)
Generation of the Cdk2ap1tm1Dtw allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdk2ap1 Mutation:  62 strains or lines available
Original:  J:146277 Kim Y, et al., Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethality. PLoS One. 2009;4(2):e4518
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory