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Cdk2ap1tm1Dtw
Targeted Allele Detail
Nomenclature
Symbol: Cdk2ap1tm1Dtw
Name: CDK2 (cyclin-dependent kinase 2)-associated protein 1; targeted mutation 1, David T Wong
MGI ID: MGI:3512185
Gene: Cdk2ap1  Location: Chr5:124345417-124363082 bp, - strand  Genetic Position: Chr5, 63.53 cM
Craniofacial abnormality of surviving Cdk2ap1tm1Dtw/Cdk2ap1tm1Dtw and Cdk2ap1tm1Dtw/Cdk2ap1+ mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146277
Parent Cell Line:  LW1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2 and 3 were replaced with a cystosine deaminase and neo cassette. (J:146277)
Generation of the Cdk2ap1tm1Dtw allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdk2ap1 Mutation:  62 strains or lines available
References
Original:  J:146277 Kim Y, et al., Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethality. PLoS One. 2009;4(2):e4518
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory