Kcnd2^tm1Ssot
Targeted Allele Detail

Summary

• Symbol: Kcnd2^tm1Ssot
• Name: potassium voltage-gated channel, Shal-related family, member 2; targeted mutation 1, Susan Sotardi
• MGI ID: MGI:3512142
• Gene: Kcnd2 Location: Chr6:21215502-21729804 bp, + strand Genetic Position: Chr6, 8.49 cM
• Alliance: Kcnd2^tm1Ssot page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin gene replaces the channel coding region from the N-terminus to the middle of the pore (Gly-373). Absence of transcript was confirmed by Northern blot analysis. (J:94338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnd2 Mutation: 30 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 1 reference(s)