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Targeted Allele Detail
Symbol: Slc3a2tm1Yai
Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; targeted mutation 1, Yasuhiko Ito
MGI ID: MGI:3511126
Synonyms: CD98-
Gene: Slc3a2  Location: Chr19:8706882-8723369 bp, - strand  Genetic Position: Chr19, 5.44 cM
Germline Transmission:  Earliest citation of germline transmission: J:93968
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsAberrant recombination resulted in the insertion of a neo cassette between intron 2 and the 5' arm of the heavy chain. Northern blot analysis showed the presence of an aberrant transcript in heterozygous mice. (J:93968)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc3a2 Mutation:  13 strains or lines available
Original:  J:93968 Tsumura H, et al., The targeted disruption of the CD98 gene results in embryonic lethality. Biochem Biophys Res Commun. 2003 Sep 5;308(4):847-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory