Tg(Myl2-FGF19)1Dfre
Transgene Detail
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Symbol: |
Tg(Myl2-FGF19)1Dfre |
Name: |
transgene insertion 1, Dorothy M French |
MGI ID: |
MGI:3510921 |
Synonyms: |
FGF19, MLC-FGFG19 |
Transgene: |
Tg(Myl2-FGF19)1Dfre Location: unknown
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Alliance: |
Tg(Myl2-FGF19)1Dfre page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Myl2-FGF19)1Dfre expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
FGF19 (9965) |
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Mutation details: The human FGF19 cDNA was ligated to a rat myosin light chain 2 promoter and followed by the splice donor/acceptor sites present between exons 4 and 5 of the human growth hormaone gene. RT-PCR analysis of skeletal muscle biopsies showed the presence of human transcript in transgenic mice. Transgenic protein was verified by enzyme-linked immunosorbent assay. This record is a representative transgene as founder lines were not named.
(J:76323)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:76323 Tomlinson E, et al., Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity. Endocrinology. 2002 May;143(5):1741-7 |
All: |
5 reference(s) |
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