About   Help   FAQ
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
Transgene Detail
Nomenclature
Symbol: Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
Name: transgene insertion, Winston C Y Yu
MGI ID: MGI:3510918
Synonyms: SIRIUS-ABCA1
Transgene: Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy  Location: unknown  
Transgene
origin
Strain of Origin:  ICR
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene consists of the mouse Rnu6 promoter, a loxP site, a CMV promoter, EGFP, and an Abca1 siRNA. Without cre mediated recombination only EGFP is expressed. After cre mediated recombination the Abca1 siRNA is expressed. Six founders were generated. (J:93624)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:93624 Chang HS, et al., Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown. Am J Pathol. 2004 Nov;165(5):1535-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/18/2019
MGI 6.14
The Jackson Laboratory