About   Help   FAQ
Traf3ip2tm1.1Lix
Targeted Allele Detail
Nomenclature
Symbol: Traf3ip2tm1.1Lix
Name: TRAF3 interacting protein 2; targeted mutation 1.1, Xiaoxia Li
MGI ID: MGI:3510784
Synonyms: Act1-
Gene: Traf3ip2  Location: Chr10:39612934-39655307 bp, + strand  Genetic Position: Chr10, 20.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93923
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsAct1tm1Lix ES cells were transfected with Cre recombinase to remove the floxed neo and exon 2. RNA blot indicated the absence of transcript in splenic B cells. (J:93923)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Traf3ip2 Mutation:  34 strains or lines available
References
Original:  J:93923 Qian Y, et al., Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Immunity. 2004 Oct;21(4):575-87
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/15/2018
MGI 6.12
The Jackson Laboratory