About   Help   FAQ
Mmp19tm1Amp
Targeted Allele Detail
Nomenclature
Symbol: Mmp19tm1Amp
Name: matrix metallopeptidase 19; targeted mutation 1, Alberto M Pendas
MGI ID: MGI:3505589
Synonyms: Mmp19-
Gene: Mmp19  Location: Chr10:128790910-128800824 bp, + strand  Genetic Position: Chr10, 77.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90802
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neo cassette replaced a 3 kb fragment containing 1 kb of the promoter and exons 1 and 2 via homologous recombination. Northern blot analysis confirmed absence of RNA in liver, lung and ovary. (J:90802)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mmp19 Mutation:  11 strains or lines available
References
Original:  J:90802 Pendas AM, et al., Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice. Mol Cell Biol. 2004 Jun;24(12):5304-13
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory