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Bcl6btm1Tto
Targeted Allele Detail
Nomenclature
Symbol: Bcl6btm1Tto
Name: B cell CLL/lymphoma 6, member B; targeted mutation 1, Takeshi Tokuhisa
MGI ID: MGI:3497910
Synonyms: BAZF-
Gene: Bcl6b  Location: Chr11:70224128-70229798 bp, - strand  Genetic Position: Chr11, 42.99 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93656
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-5, including the ATG were replaced with a neomycin resistance gene. mRNA was not detected in any tissues examined by Northern blot. (J:93656)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl6b Mutation:  2 strains or lines available
References
Original:  J:93656 Takamori M, et al., BAZF is required for activation of naive CD4 T cells by TCR triggering. Int Immunol. 2004 Oct;16(10):1439-49
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory