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Tg(Pcp2-cre)22Lfr
Transgene Detail
Summary
Symbol: Tg(Pcp2-cre)22Lfr
Name: transgene insertion 22, Louis F Reichardt
MGI ID: MGI:3056290
Synonyms: TG-L7creLFR22
Transgene: Tg(Pcp2-cre)22Lfr  Location: unknown  
Alliance: Tg(Pcp2-cre)22Lfr page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pcp2-cre)22Lfr expression driven by 1 gene
 
Mutation detailsA nuclear localization signal-Kozak sequence-cre-protamine 1 construct was inserted into the fourth exon of the Purkinje cell protein 2 gene, which targets Cre recombinase expression exclusively to Purkinje cells. (J:92042)
Recombinase
activity
Activity:
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Driver: Pcp2 (species not specified)
Summary of all recombinase alleles driven by Pcp2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:92042 Braz JM, et al., Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15148-53
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory